
Researchers at Stanford and the Arc Institute have successfully used AI to design viruses that are not found in nature, aiming to combat drug-resistant bacterial infections. The AI models, Evo 1 and Evo 2, were trained on millions of genomes to create new versions of the Phi X174 virus, resulting in 16 viable viruses. These AI-designed viruses were able to eliminate E. coli strains resistant to natural viruses. While the development is a significant step forward in addressing antibiotic resistance, it also underscores the need for careful regulation to prevent potential misuse.
Read original
© Hugging Face BlogTutorMoments, a new framework from Hugging Face, aims to assess how well AI tutors can balance helping students and encouraging independent problem-solving. By using real math tutoring transcripts, the framework evaluates language models on their ability to make pedagogical decisions at key moments. The findings reveal that while AI models tend to over-help, explicit prompts about when to assist or hold back improve their performance. However, there's still a significant gap between AI and human tutors in adapting to students' needs, highlighting the complexity of effective tutoring.
Stanford's Evo 2 AI model has made a significant leap in synthetic biology by generating phages that effectively target E. coli. This breakthrough demonstrates the potential of AI to design entire viral genomes, moving beyond simple DNA edits. The model produced thousands of candidate genomes, with 16 showing strong E. coli-killing activity in lab tests. By releasing Evo 2 as open-source software, Stanford is inviting further exploration and innovation in genome design, potentially paving the way for new treatments against resistant bacteria like MRSA.